Active Research Projects

PI: Charlene Pringle

Development and Validation of a Nutrition Screening Tool for Critically Ill Children

Multi-center phase II validation of a novel screening tool for malnutrition in critically ill children.

PI: Charlene Pringle

Pediatric TBI Repository

The overall goal of this study is to create a pediatric TBI biorepository that will serve as a platform for a systematic, multimodal assessment of severity and outcome at the University of Florida.

PI: Torrey Baines

PERSEVERE (Genomic analysis of pediatric systemic inflammatory response syndrome)

Multicenter study including patients 1 months to 10 years of age admitted to the PICU with SIRS or sepsis. The purpose of the study is to determine if outcomes in pediatric sepsis are influence by any specific genetic makeup of the individual.

PI: Charlene Pringle | Sub-I: Manuel Viamonte

Peds PRES

Large case series of pediatric patients with hypertensive encephalopathy aiming to better describe risk factors and correlations.

PI: Maria Kerrigan

Music for delirium management in pediatric critical care

Prospective, interventional study assessing impact of music on development of ICU delirium.

PI: William Bortcosh

High-Fidelity Simulation Training for Parents of Medically Complex Children

Single-center, non-randomized prospective trial implementing simulation training for parents who will be discharged from the PICU with a child with a new tracheostomy.

PI: Desiree Machado

Blood product utilization in pediatric ECMO

A before and after study after standardization of transfusion practices.

PI: Charlene Pringle

nTBI (Nutrition and Pediatric TBI)

Retrospective review of the impact of timing of enteral nutrition on short and long-term outcomes after TBI

PI: Charlene Pringle

EN vs dexmedetomidine and NIV (Impact of enteral nutrition on dexmedetomidine usage in critically ill children requiring NIV)

Retrospective convenience sample comparing sedation requirements of children acutely requiring NIV with and without enteral nutrition

PI: CHARLENE PRINGLE

Death One Hour After Terminal Extubation (DONATE) Study

Multi-centric validation of model developed by CHLA to predict death within one hour of terminal extubation

PI: Leslie Avery

ICARE (The Interdisciplinary Cardiac Arrest Research Review)

The Interdisciplinary Cardiac Arrest Research Review (ICARE) group was formed in 2018 to conduct a systematic annual search of peer-reviewed literature relevant to cardiac arrest (CA). The goals of the review are to illustrate best practices and help reduce knowledge silos by disseminating clinically relevant advances in the field of CA across disciplines.

PI: Emily Plowman and Desiree Machado (Wang fellow project)

Post-extubation dysphagia in children after mechanical ventilatory support

PI: DESIREE Machado

Machine-learning prediction protocol for anticoagulation with bivalirudin in children on ECMO

PI: Giles Peek (Vazquez-Colon fellow project

Tethered liquid perfluorocarbon (TLP) surface coating for ECMO tubing, In-vitro model using human blood