ABC PICU (Age of Blood in Children in Pediatric Intensive Care Units)
CO-PI: Leslie Avery, MD; Peter Pelletier, MD
Multicenter (>40 children’s hospitals) randomized clinical trial comparing the clinical consequences of RBC storage duration in 1538 critically ill children.
COBO2 (Continuous vs BOlus Nasogastric Feeding in Mechanically Ventilated Pediatric Patients 2
CO-PI: Torrey Baines, MD; Charlene Leonard, APRN
Multicenter (7 children’s hospitals) randomized clinical trial comparing continuous versus bolus gastric feeding modes for timing and delivery of prescribed energy (kcal/kg/day) and protein (g/kg/day) for over 200 mechanically ventilated children 1 month through 12 years of age.
Continuous Albuterol (FM vs HFNC)
CO-PI: Nekaiya Jacobs, MD; Jennifer Munoz, MD
Single center observational study comparing outcomes of high flow nasal cannula and face mask for continuous albuterol delivery and association with length of stay, asthma scores, and need for escalation of therapy
Thenar tissue oxygenation (StO2): A non-invasive surrogate marker for central venous oxygen saturation.
PI: Ravi Samraj
Study comparing thenar tissue oxygenation device with traditional central venous oxygen saturations in critically ill children.
CO-PI: Molly Mcgetrick, MD; Jennifer Munoz, MD
Single center, CAPD scoring for up to 7 days on most PICU and PCICU patients to define prevalence of delirium in our patient population
Multi-center phase II validation of a novel screening tool for malnutrition in critically ill children.
Multi-center/PALISI period prevalence study about long term mechanical ventilation.
The overall goal of this study is to create a pediatric TBI biorepository that will serve as a platform for a systematic, multimodal assessment of severity and outcome at the University of Florida.
Identification of autoimmune central nervous system diseases via flow cytometry.
Multicenter study including patients 1 months to 10 years of age admitted to the PICU with SIRS or sepsis. The purpose of the study is to determine if outcomes in pediatric sepsis are influence by any specific genetic makeup of the individual.
Multicenter (>80 children’s hospitals) period prevalence study evaluation nutiritional practices and patient outcomes across global regions for enteral and parenteral nutrition for infants and children initiated on NIV (BiPAP, CPAP, HFNC) for six 7 day study periods over 2017 and 2018.
Multicenter (~50 PICUs) 2×2 factorial, response adaptive randomized clinical trial of supine/prone positioning and CMV/HFOV for pediatric patients with severe pARDS.
Large case series of pediatric patients with hypertensive encephalopathy aiming to better describe risk factors and correlations.
Study examining vascular occlusion test and outcomes in pediatric sepsis.